9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione 21-acetate
9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione 21-acetate
CAS: 3859-65-2
Molecular Formula: C23H29FO7
9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione 21-acetate - Names and Identifiers
9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione 21-acetate - Physico-chemical Properties
| Molecular Formula | C23H29FO7 |
| Molar Mass | 436.47 |
| Physical and Chemical Properties | Chemical properties crystallization. Melting point 203 ℃. |
| Use | Uses the intermediate of Yiyan-Shusong. |
9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione 21-acetate - Production method
11 α,17 α,21-trihydroxypregnoline-4-ene-3, 20-dione (I. e. epihydrocortisone) can be acetylated by (21-hydroxy), (11-hydroxy) sulfonylation and elimination to generate 17 α,21-dihydroxypregnoline-4, 9(11) diene -3,20-diketone -17 α,21-diacetate, then by [9(11)-position double bond hypobromic acid] addition and epoxidation, (hydrogen fluoride on epoxy group) addition (9-position fluorine), dehydrogenation (formation 4-position double bond), elimination (16,17-position deacetate to form double bond), (16-position double bond) oxidation to obtain the product.
Last Update：2024-04-09 21:01:54
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Spot supply
Product Name: Triamcinolone Impurity 2 (Triamcinolone EP Impurity B) Visit Supplier Webpage Request for quotationCAS: 3859-65-2
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
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